Anna-Lisa Doebley

Graduate Student

Joined March 2019

Email
adoebleyobfuscate@fredhutch.org

I am a student in the MSTP program at the University of Washington. I got my bachelor’s degree from the University of Wisconsin – Madison where I majored in Genetics and minored in Painting. While at the University of Wisconsin, I did research in Dr. Akihiro Ikeda’s lab where I studied the genetic causes of corneal neovascularization (a cancer like phenotype in the mouse eye) and retinal degeneration (which is similar to macular degeneration in humans). During my undergraduate studies, I also spent time at UNC Chapel Hill where I worked in Dr. Shawn Ahmed’s lab and studied aging using mortal germline mutants in C. elegans. These research experiences lead me to pursue an MD-PhD so that I could continue working on genetic research and help bridge the gap between research and the clinic.

As a graduate student, I became interested in computational methods for genetic research. I’m especially interested in using these methods to improve cancer detection, prognosis, and treatment. In the Ha lab, I am looking forward to learning more about computational and mathematical approaches to cancer genomics and utilizing these approaches to improve cancer detection in cell free DNA.

Outside of the lab, I enjoy arts and crafts, singing, reading, and outdoor adventures.

Papers

Nucleosome patterns in circulating tumor DNA reveal transcriptional regulation of advanced prostate cancer phenotypes

Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa

Griffin: Framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA

Software & Code

Griffin